Molecular Background of Leak K + Currents: Two-Pore Domain Potassium Channels

Two-pore domain K + (K 2P ) channels give rise to leak (also called background) K + currents. The well-known role of background K + currents is to stabilize the negative resting membrane potential and counterbalance depolarization. However, it has become apparent in the past decade (during the detai...

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Bibliographic Details
Published in:Physiological reviews 2010-04, Vol.90 (2), p.559-605
Main Authors: Enyedi, Péter, Czirják, Gábor
Format: Article
Language:English
Subjects:
Animals
Cells
Gene Expression Regulation - physiology
Humans
Membrane Potentials - physiology
Membranes
Molecular structure
Multigene Family
Physiology
Potassium
Potassium - metabolism
Potassium Channels, Inwardly Rectifying - metabolism
Signal transduction
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