Specificity of Staphylococcal Superantigen-Like Protein 10 toward the Human IgG1 Fc Domain

Staphylococcal superantigen-like protein 10 (SSL10) is a highly conserved member of the SSL family secreted by Staphylococcus aureus that displays structural but not functional similarity to superantigens. SSL10 bound to fibrinogen and fibronectin from plasma and in addition displayed striking speci...

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Bibliographic Details
Published in:The Journal of immunology (1950) 2010-06, Vol.184 (11), p.6283-6292
Main Authors: Patel, Deepa, Wines, Bruce D, Langley, Ries J, Fraser, John D
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Antibody Specificity - immunology
Bacterial Proteins - genetics
Bacterial Proteins - immunology
Bacterial Proteins - metabolism
Blotting, Western
Cattle
Cell Separation
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Guinea Pigs
Humans
Immunoglobulin Fc Fragments - immunology
Immunoglobulin Fc Fragments - metabolism
Immunoglobulin G - immunology
Immunoglobulin G - metabolism
Immunoprecipitation
Mice
Molecular Sequence Data
Polymerase Chain Reaction
Rabbits
Sequence Homology, Amino Acid
Species Specificity
Staphylococcus aureus - immunology
Staphylococcus aureus - metabolism
Staphylococcus aureus - pathogenicity
Superantigens - genetics
Superantigens - immunology
Superantigens - metabolism
Virulence Factors
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