Lansoprazole for Children With Poorly Controlled Asthma: A Randomized Controlled Trial

CONTEXT Asymptomatic gastroesophageal reflux (GER) is prevalent in children with asthma. Untreated GER has been postulated to be a cause of inadequate asthma control in children despite inhaled corticosteroid treatment, but it is not known whether treatment with proton pump inhibitors improves asthm...

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Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2012-01, Vol.307 (4), p.373-380
Main Author: American Lung Association Asthma Clinical Research Centers, Writing Committee for the
Format: Article
Language:English
Subjects:
2-Pyridinylmethylsulfinylbenzimidazoles - adverse effects
2-Pyridinylmethylsulfinylbenzimidazoles - therapeutic use
Administration, Inhalation
Adolescent
Adrenal Cortex Hormones - administration & dosage
Asthma
Asthma - drug therapy
Asthma - physiopathology
Biological and medical sciences
Child
Children & youth
Chronic obstructive pulmonary disease, asthma
Clinical trials
Double-Blind Method
Enzyme Inhibitors - adverse effects
Enzyme Inhibitors - therapeutic use
Female
Gastroesophageal Reflux
General aspects
Humans
Lansoprazole
Lung - drug effects
Lung - physiopathology
Male
Medical sciences
Pneumology
Proton Pump Inhibitors
Quality of Life
Respiratory Function Tests
Respiratory Tract Infections - chemically induced
Treatment Outcome
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