Risk factors for surgical site infection after gastric surgery: A multicentre case-control study

Abstract Background: Surgical site infection (SSI) is a potentially morbid and costly complication of surgery. We conducted a multicentre case-control study to determine the risk factors for SSI in patients undergoing gastric surgery and to establish strategies to reduce the risk of SSI. Methods: Be...

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Published in:Scandinavian journal of infectious diseases 2012-06, Vol.44 (6), p.419-426
Main Authors: Jeong, Su Jin, Kim, Chang Oh, Han, Sang Hoon, Choi, Jun Yong, Kim, Min Ja, Choi, Young Hwa, Lim, Seung-Kwan, Yeom, Joon-Sup, Park, Yoon Soo, Song, Young Goo, Choi, Hee Jung, Peck, Kyong Ran, Kang, Cheol-In, Kim, Hyo-Youl, Kim, Young-Keun, Lee, Seung Soon, Park, Dae-Won, Kim, Yeon-A, Choi, Suk-Hoon, Kim, June Myung
Format: Article
Language:English
Subjects:
Aged
Case-Control Studies
Digestive System Surgical Procedures - adverse effects
Female
gastric surgery
Humans
Male
Middle Aged
Republic of Korea - epidemiology
Risk Factors
Stomach Diseases - surgery
Surgical site infection
Surgical Wound Infection - epidemiology
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Summary:Abstract Background: Surgical site infection (SSI) is a potentially morbid and costly complication of surgery. We conducted a multicentre case-control study to determine the risk factors for SSI in patients undergoing gastric surgery and to establish strategies to reduce the risk of SSI. Methods: Between January 2007 and December 2008, 121 patients who developed an SSI after gastric surgery were matched with controls who had undergone surgery on the dates closest to those of the cases, at 13 centres in Korea. Results: The results of multivariate analyses showed that the independent risk factors for SSI after gastric surgery were older age (p = 0.016), higher body mass index (BMI) (p = 0.033), male gender (p = 0.047), and longer duration of prophylactic antibiotic use (p < 0.001). Conclusion: Older age, higher BMI, male gender, and longer duration of prophylactic antibiotic use were independently associated with significant increases in the risk of SSI. Additional prospective randomized studies are required to confirm these results.
ISSN:0036-5548
1651-1980
DOI:10.3109/00365548.2011.652159