Antiphytopathogenic activity of Psoralea glandulosa (Fabaceae) against Botrytis cinerea and Phytophthora cinnamomi

The resinous exudate, three meroterpenes, namely bakuchiol (1), 3-hydroxybakuchiol (2), 12-hydroxyisobakuchiol (3), and one furanocoumarin, psoralen (4), were isolated from the leaves of culen (Psoralea glandulosa). In addition to these, two semi-synthetic derivatives, bakuchiol acetate (5) and baku...

Full description

Saved in:
Bibliographic Details
Published in:Natural product research 2015-03, Vol.29 (6), p.586-588
Main Authors: Madrid Villegas, Alejandro, Díaz Peralta, Katy, González Tapia, César, Catalán Marín, Karen, Espinoza Catalán, Luis
Format: Article
Language:English
Subjects:
antifungal
Antifungal Agents - pharmacology
bakuchiol
Botrytis - drug effects
Catechols - chemistry
Ficusin - chemistry
Furocoumarins - chemistry
Monoterpenes - chemistry
Monoterpenes - pharmacology
Phenols - chemistry
Phytophthora - drug effects
Plant Leaves - chemistry
Psoralea - chemistry
Psoralea glandulosa
psoralen
resinous exudate
Resins, Plant - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The resinous exudate, three meroterpenes, namely bakuchiol (1), 3-hydroxybakuchiol (2), 12-hydroxyisobakuchiol (3), and one furanocoumarin, psoralen (4), were isolated from the leaves of culen (Psoralea glandulosa). In addition to these, two semi-synthetic derivatives, bakuchiol acetate (5) and bakuchiol methyl eter (6), were obtained from 1, and were subsequently evaluated in vitro for the inhibitory effect of resin and compounds on the mycelial growth of Botrytis cinerea Pers.: Fr. and Phytophthora cinnamomi Rands. The resinous exudate inhibited the mycelial growth of both the pathogens, while bakuchiol (1) exhibited an inhibitory effect on the mycelial growth of B. cinerea up to 94% at a concentration of 150 mg/L and psoralen (4) reduced the mycelial growth of P. cinnamomi up to 80% at a concentration of 150 mg/L. These compounds have the ability of blocking the development of mycelial growth and may be used as a potential biopesticide in the agricultural sector once the in vivo test results have been validated.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2014.955486