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Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment
Blood pressure (BP) control throughout the entire day is recommended for cardiovascular protection. Angiotensin-II receptor blockers (ARBs) are widely used in hypertensive patients because of beneficial class effects. It is uncertain, however, whether are there any differences in 24-h BP profiles am...
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| Published in: | Clinical and experimental hypertension (1993) 2015-10, Vol.37 (7), p.574-579 |
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| container_end_page | 579 |
| container_issue | 7 |
| container_start_page | 574 |
| container_title | Clinical and experimental hypertension (1993) |
| container_volume | 37 |
| creator | Kita, Toshihiro Sakima, Atsushi Yokota, Naoto Tamaki, Noboru Etoh, Takuma Shimokubo, Toru Nakada, Seigo Takishita, Shuichi Ohya, Yusuke Kitamura, Kazuo |
| description | Blood pressure (BP) control throughout the entire day is recommended for cardiovascular protection. Angiotensin-II receptor blockers (ARBs) are widely used in hypertensive patients because of beneficial class effects. It is uncertain, however, whether are there any differences in 24-h BP profiles among ARBs. We examined ambulatory blood pressure monitoring (ABPM) among 211 Japanese hypertensive patients (age, 69.4 ± 9.6 years; female, 59.2%) under treatment with five different ARBs. Patients were divided into five groups according to ARBs prescribed. Patient backgrounds were almost identical in all the groups and there were no differences in office, 24-h and daytime BP; however, nighttime BP with olmesartan was significantly lower than with other ARBs. Office BPs with candesartan and telmisartan, but not other ARBs, correlated well with 24-h BP (p |
| doi_str_mv | 10.3109/10641963.2015.1026042 |
| format | article |
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Angiotensin-II receptor blockers (ARBs) are widely used in hypertensive patients because of beneficial class effects. It is uncertain, however, whether are there any differences in 24-h BP profiles among ARBs. We examined ambulatory blood pressure monitoring (ABPM) among 211 Japanese hypertensive patients (age, 69.4 ± 9.6 years; female, 59.2%) under treatment with five different ARBs. Patients were divided into five groups according to ARBs prescribed. Patient backgrounds were almost identical in all the groups and there were no differences in office, 24-h and daytime BP; however, nighttime BP with olmesartan was significantly lower than with other ARBs. Office BPs with candesartan and telmisartan, but not other ARBs, correlated well with 24-h BP (p < 0.01). Also, there were higher correlations between daytime and nighttime BP with candesartan and telmisartan. In all patients, pulse pressure with office BP was significantly correlated with ambulatory arterial stiffness index (p = 0.001) and fluctuation of systolic BP on ABPM (p = 0.002). In conclusion, different ARB treatments produced meaningful differences in 24-h profiles.</description><identifier>ISSN: 1064-1963</identifier><identifier>EISSN: 1525-6006</identifier><identifier>DOI: 10.3109/10641963.2015.1026042</identifier><identifier>PMID: 25992487</identifier><language>eng</language><publisher>England: Informa Healthcare</publisher><subject>Aged ; ambulatory blood pressure monitoring ; Angiotensin Receptor Antagonists - administration & dosage ; Angiotensin Receptor Antagonists - pharmacokinetics ; Angiotensin-II receptor blocker ; Benzimidazoles - administration & dosage ; Benzimidazoles - pharmacokinetics ; Blood Pressure - drug effects ; Blood Pressure Monitoring, Ambulatory - methods ; Cross-Sectional Studies ; Female ; Humans ; hypertension ; Hypertension - drug therapy ; Hypertension - epidemiology ; Hypertension - physiopathology ; Imidazoles - administration & dosage ; Imidazoles - pharmacokinetics ; Japan - epidemiology ; Japanese ; Male ; Middle Aged ; pulse pressure ; Tetrazoles - administration & dosage ; Tetrazoles - pharmacokinetics ; Therapeutic Equivalency</subject><ispartof>Clinical and experimental hypertension (1993), 2015-10, Vol.37 (7), p.574-579</ispartof><rights>2015 Taylor & Francis Group, LLC. 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c450t-bbc61386b12a190845800bb9704478d3033250adc872f48181d37cb80ea57b413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25992487$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kita, Toshihiro</creatorcontrib><creatorcontrib>Sakima, Atsushi</creatorcontrib><creatorcontrib>Yokota, Naoto</creatorcontrib><creatorcontrib>Tamaki, Noboru</creatorcontrib><creatorcontrib>Etoh, Takuma</creatorcontrib><creatorcontrib>Shimokubo, Toru</creatorcontrib><creatorcontrib>Nakada, Seigo</creatorcontrib><creatorcontrib>Takishita, Shuichi</creatorcontrib><creatorcontrib>Ohya, Yusuke</creatorcontrib><creatorcontrib>Kitamura, Kazuo</creatorcontrib><title>Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment</title><title>Clinical and experimental hypertension (1993)</title><addtitle>Clin Exp Hypertens</addtitle><description>Blood pressure (BP) control throughout the entire day is recommended for cardiovascular protection. Angiotensin-II receptor blockers (ARBs) are widely used in hypertensive patients because of beneficial class effects. It is uncertain, however, whether are there any differences in 24-h BP profiles among ARBs. We examined ambulatory blood pressure monitoring (ABPM) among 211 Japanese hypertensive patients (age, 69.4 ± 9.6 years; female, 59.2%) under treatment with five different ARBs. Patients were divided into five groups according to ARBs prescribed. Patient backgrounds were almost identical in all the groups and there were no differences in office, 24-h and daytime BP; however, nighttime BP with olmesartan was significantly lower than with other ARBs. Office BPs with candesartan and telmisartan, but not other ARBs, correlated well with 24-h BP (p < 0.01). Also, there were higher correlations between daytime and nighttime BP with candesartan and telmisartan. In all patients, pulse pressure with office BP was significantly correlated with ambulatory arterial stiffness index (p = 0.001) and fluctuation of systolic BP on ABPM (p = 0.002). In conclusion, different ARB treatments produced meaningful differences in 24-h profiles.</description><subject>Aged</subject><subject>ambulatory blood pressure monitoring</subject><subject>Angiotensin Receptor Antagonists - administration & dosage</subject><subject>Angiotensin Receptor Antagonists - pharmacokinetics</subject><subject>Angiotensin-II receptor blocker</subject><subject>Benzimidazoles - administration & dosage</subject><subject>Benzimidazoles - pharmacokinetics</subject><subject>Blood Pressure - drug effects</subject><subject>Blood Pressure Monitoring, Ambulatory - methods</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>hypertension</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - epidemiology</subject><subject>Hypertension - physiopathology</subject><subject>Imidazoles - administration & dosage</subject><subject>Imidazoles - pharmacokinetics</subject><subject>Japan - epidemiology</subject><subject>Japanese</subject><subject>Male</subject><subject>Middle Aged</subject><subject>pulse pressure</subject><subject>Tetrazoles - administration & dosage</subject><subject>Tetrazoles - pharmacokinetics</subject><subject>Therapeutic Equivalency</subject><issn>1064-1963</issn><issn>1525-6006</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kE1r3DAQhkVpaD7an9CiYy_ejL5s-dZ8pyEQCOlZlewRUbGtrWQn7L-vlt3k2NMMwzMzLw8hXxmsBIP2lEEtWVuLFQemVgx4DZJ_IEdMcVXVAPXH0hem2kKH5DjnPwBM1kp_IodctS2Xujkivy-D95hw6jDTMFEuq2fqhhh7uk6Y85KwNNGHAWn09M6u7YQZ6fNmjWnGKYeXAtg54DRnukw9Jnr2eE7nhHYey_AzOfB2yPhlX0_Ir-urp4vb6v7h5ufF2X3VSQVz5VxXM6Frx7hlLWipNIBzbQNSNroXIARXYPtON9xLzTTrRdM5DWhV4yQTJ-T77m5J-3fBPJsx5A6HoeSNSzas4U3bimKgoGqHdinmnNCbdQqjTRvDwGzlmje5ZivX7OWWvW_7F4sbsX_ferNZgB87IEw-ptG-xjT0ZrabISaf7NSFvL3_vx__AAarh6U</recordid><startdate>20151003</startdate><enddate>20151003</enddate><creator>Kita, Toshihiro</creator><creator>Sakima, Atsushi</creator><creator>Yokota, Naoto</creator><creator>Tamaki, Noboru</creator><creator>Etoh, Takuma</creator><creator>Shimokubo, Toru</creator><creator>Nakada, Seigo</creator><creator>Takishita, Shuichi</creator><creator>Ohya, Yusuke</creator><creator>Kitamura, Kazuo</creator><general>Informa Healthcare</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151003</creationdate><title>Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment</title><author>Kita, Toshihiro ; Sakima, Atsushi ; Yokota, Naoto ; Tamaki, Noboru ; Etoh, Takuma ; Shimokubo, Toru ; Nakada, Seigo ; Takishita, Shuichi ; Ohya, Yusuke ; Kitamura, Kazuo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-bbc61386b12a190845800bb9704478d3033250adc872f48181d37cb80ea57b413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>ambulatory blood pressure monitoring</topic><topic>Angiotensin Receptor Antagonists - administration & dosage</topic><topic>Angiotensin Receptor Antagonists - pharmacokinetics</topic><topic>Angiotensin-II receptor blocker</topic><topic>Benzimidazoles - administration & dosage</topic><topic>Benzimidazoles - pharmacokinetics</topic><topic>Blood Pressure - drug effects</topic><topic>Blood Pressure Monitoring, Ambulatory - methods</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>hypertension</topic><topic>Hypertension - drug therapy</topic><topic>Hypertension - epidemiology</topic><topic>Hypertension - physiopathology</topic><topic>Imidazoles - administration & dosage</topic><topic>Imidazoles - pharmacokinetics</topic><topic>Japan - epidemiology</topic><topic>Japanese</topic><topic>Male</topic><topic>Middle Aged</topic><topic>pulse pressure</topic><topic>Tetrazoles - administration & dosage</topic><topic>Tetrazoles - pharmacokinetics</topic><topic>Therapeutic Equivalency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kita, Toshihiro</creatorcontrib><creatorcontrib>Sakima, Atsushi</creatorcontrib><creatorcontrib>Yokota, Naoto</creatorcontrib><creatorcontrib>Tamaki, Noboru</creatorcontrib><creatorcontrib>Etoh, Takuma</creatorcontrib><creatorcontrib>Shimokubo, Toru</creatorcontrib><creatorcontrib>Nakada, Seigo</creatorcontrib><creatorcontrib>Takishita, Shuichi</creatorcontrib><creatorcontrib>Ohya, Yusuke</creatorcontrib><creatorcontrib>Kitamura, Kazuo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental hypertension (1993)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kita, Toshihiro</au><au>Sakima, Atsushi</au><au>Yokota, Naoto</au><au>Tamaki, Noboru</au><au>Etoh, Takuma</au><au>Shimokubo, Toru</au><au>Nakada, Seigo</au><au>Takishita, Shuichi</au><au>Ohya, Yusuke</au><au>Kitamura, Kazuo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment</atitle><jtitle>Clinical and experimental hypertension (1993)</jtitle><addtitle>Clin Exp Hypertens</addtitle><date>2015-10-03</date><risdate>2015</risdate><volume>37</volume><issue>7</issue><spage>574</spage><epage>579</epage><pages>574-579</pages><issn>1064-1963</issn><eissn>1525-6006</eissn><abstract>Blood pressure (BP) control throughout the entire day is recommended for cardiovascular protection. Angiotensin-II receptor blockers (ARBs) are widely used in hypertensive patients because of beneficial class effects. It is uncertain, however, whether are there any differences in 24-h BP profiles among ARBs. We examined ambulatory blood pressure monitoring (ABPM) among 211 Japanese hypertensive patients (age, 69.4 ± 9.6 years; female, 59.2%) under treatment with five different ARBs. Patients were divided into five groups according to ARBs prescribed. Patient backgrounds were almost identical in all the groups and there were no differences in office, 24-h and daytime BP; however, nighttime BP with olmesartan was significantly lower than with other ARBs. Office BPs with candesartan and telmisartan, but not other ARBs, correlated well with 24-h BP (p < 0.01). Also, there were higher correlations between daytime and nighttime BP with candesartan and telmisartan. In all patients, pulse pressure with office BP was significantly correlated with ambulatory arterial stiffness index (p = 0.001) and fluctuation of systolic BP on ABPM (p = 0.002). In conclusion, different ARB treatments produced meaningful differences in 24-h profiles.</abstract><cop>England</cop><pub>Informa Healthcare</pub><pmid>25992487</pmid><doi>10.3109/10641963.2015.1026042</doi><tpages>6</tpages></addata></record> |
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| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Aged ambulatory blood pressure monitoring Angiotensin Receptor Antagonists - administration & dosage Angiotensin Receptor Antagonists - pharmacokinetics Angiotensin-II receptor blocker Benzimidazoles - administration & dosage Benzimidazoles - pharmacokinetics Blood Pressure - drug effects Blood Pressure Monitoring, Ambulatory - methods Cross-Sectional Studies Female Humans hypertension Hypertension - drug therapy Hypertension - epidemiology Hypertension - physiopathology Imidazoles - administration & dosage Imidazoles - pharmacokinetics Japan - epidemiology Japanese Male Middle Aged pulse pressure Tetrazoles - administration & dosage Tetrazoles - pharmacokinetics Therapeutic Equivalency |
| title | Differences in 24-h blood pressure profile of Japanese hypertensive patients under ARB treatment |
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