Long‐acting beta2‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta2‐agonist alone for chronic obstructive pulmonary disease

Background Long‐acting bronchodilators, comprising long‐acting beta2‐agonists (LABA) and long‐acting anti‐muscarinic agents (LAMA, principally tiotropium), are commonly used for managing persistent symptoms of chronic obstructive pulmonary disease (COPD). Combining these treatments, which have diffe...

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Bibliographic Details
Published in:	Cochrane database of systematic reviews 2015-10, Vol.2015 (10), p.CD008989
Main Authors:	Farne, Hugo A, Cates, Christopher J
Format:	Article
Language:	English
Subjects:	Adrenergic beta-2 Receptor Agonists - therapeutic use Adrenergic beta‐2 Receptor Agonists Aged Albuterol Albuterol - analogs & derivatives Albuterol - therapeutic use Beta‐agonists, long‐acting, twice daily Bronchodilator Agents Bronchodilator Agents - therapeutic use Bronchodilators Chronic obstructive pulmonary disease (stable) Chronic obstructive pulmonary disease, stable ‐ pharmacotherapy Combination and additive therapies Combination/additive drug treatment Ethanolamines Ethanolamines - therapeutic use Formoterol Fumarate Formoterol Fumarate - therapeutic use Humans Indans Indans - therapeutic use Lungs & airways Medicine General & Introductory Medical Sciences Middle Aged Muscarinic antagonists Pulmonary Disease, Chronic Obstructive Pulmonary Disease, Chronic Obstructive - drug therapy Quality of Life Quinolones Quinolones - therapeutic use Randomized Controlled Trials as Topic Salmeterol Xinafoate Salmeterol Xinafoate - therapeutic use Scopolamine Derivatives Scopolamine Derivatives - therapeutic use Tiotropium Bromide Tiotropium Bromide - therapeutic use
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