Unimolecular Polypharmacy for Treatment of Diabetes and Obesity

Many complex diseases have historically proven to be defiant to the best mono-therapeutic approaches. Several examples of combination therapies have largely overcome such challenges, notably for the treatment of severe hypertension and tuberculosis. Obesity and its consequences, such as type 2 diabe...

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Bibliographic Details
Published in:Cell metabolism 2016-07, Vol.24 (1), p.51-62
Main Authors: Tschöp, Matthias H., Finan, Brian, Clemmensen, Christoffer, Gelfanov, Vasily, Perez-Tilve, Diego, Müller, Timo D., DiMarchi, Richard D.
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Bariatric Surgery
Diabetes Mellitus, Type 2 - drug therapy
Glucagon - metabolism
Humans
Obesity - drug therapy
Peptides - chemistry
Peptides - metabolism
Polypharmacy
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