Prognostic value of CHA2DS2-VASc score in patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention

• Published in: Acta Cardiologica 2016-12, Vol.71 (6), p.663-669
• Main Authors: Satilmisoglu, Muhammet Hulusi, Gul, Mehmet, Yildiz, Gunduz, Akgul, Ozgur, Kaya, Mehmet, Cakmak, Hüseyin Altug, Akkaya, Emre, Aslan, Serkan, Ameri, Mohammad Toib, Ozyilmaz, Sinem Ozbay, Yildirim, Aydin
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Mortality; myocardial infarction; Percutaneous Coronary Intervention; Prognosis; Retrospective Studies; Risk Assessment; risk score; ST Elevation Myocardial Infarction - mortality; ST Elevation Myocardial Infarction - surgery; Survival Rate
• ISSN: 0001-5385; 1784-973X; 0373-7934
• DOI: 10.1080/AC.71.6.3178184

Objectives The aim of the study was to investigate the relationship between CHA2DS2-VASc score and in-hospital and long-term all-cause and cardiovascular mortality in patients with STEMI who underwent primary PCI. Methods In this retrospective study, 604 patients, admitted to the emergency department with a diagnosis of STEMI, were included. The study patients were divided into three risk groups according to CHA2DS2-VASc score: low-risk group (1 point), moderate-risk group (2 points), and high-risk group (3 points and higher), respectively. Results The mean follow-up time was 680 ± 286 days. In the high-risk group, the rates of in-hospital and long-term all-cause and cardiovascular mortality were higher than in the other groups. The Kaplan-Meier curves for the group with CHA2DS2-VASc scores > 2 indicated a significantly shorter long-term survival (P 2 were identified as an effective predictive cut-off point for all-cause mortality in STEMI (area under curve = 0.850, 95% confidence interval: 0.819-0.878, P< 0.001). CHA2DS2-VASc score > 2 yielded a sensitivity of 70.18% and a specificity of 83%. Conclusion The CHA2DS2-VASc is a simple and easily calculated score that provides an additional level of risk stratification beyond that provided by conventional risk scores in predicting in-hospital and long-term all-cause and cardiovascular mortality in STEMI.