Macro‐ and microvascular endothelial dysfunction in diabetes

Highlights Diabetes affects endothelial function in both large blood vessels and the microvasculature. Diabetes‐induced endothelial dysfunction, especially in the microvasculature, is characterized by reduced nitric oxide (NO) bioavailability, increased oxidative stress, an imbalance between vascula...

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Bibliographic Details
Published in:	Journal of diabetes 2017-05, Vol.9 (5), p.434-449
Main Authors:	Shi, Yi, Vanhoutte, Paul M.
Format:	Article
Language:	English
Subjects:	Animals Blood Vessels - physiopathology Circulatory system Diabetes Diabetes Mellitus - physiopathology Diabetic Angiopathies - genetics Diabetic Angiopathies - metabolism Diabetic Angiopathies - physiopathology endothelial cells Endothelium Endothelium, Vascular - physiopathology Humans MicroRNAs MicroRNAs - genetics microvasculature Microvessels - physiopathology miRNA nitric oxide Nitric Oxide - metabolism Oxidative Stress 一氧化氮微循环血管组织糖尿病血管内皮细胞
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