The Spatiotemporal Limits of Developmental Erk Signaling

Animal development is characterized by signaling events that occur at precise locations and times within the embryo, but determining when and where such precision is needed for proper embryogenesis has been a long-standing challenge. Here we address this question for extracellular signal regulated k...

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Bibliographic Details
Published in:Developmental cell 2017-01, Vol.40 (2), p.185-192
Main Authors: Johnson, Heath E., Goyal, Yogesh, Pannucci, Nicole L., Schüpbach, Trudi, Shvartsman, Stanislav Y., Toettcher, Jared E.
Format: Article
Language:English
Subjects:
Animals
Drosophila
Drosophila melanogaster - embryology
Drosophila melanogaster - enzymology
Drosophila melanogaster - genetics
embryogenesis
Embryonic Development - genetics
Embryonic Development - radiation effects
Enzyme Activation - radiation effects
Extracellular Signal-Regulated MAP Kinases - metabolism
Gene Expression Regulation, Developmental - radiation effects
Light
MAP kinase
MAP Kinase Signaling System
Optogenetics
ras Proteins - metabolism
signal transduction
Time Factors
Transcription, Genetic - radiation effects
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