Candida colonisation in asymptomatic HIV patients attending a tertiary hospital in Benin City, Nigeria

Candidiasis is the commonest opportunistic fungal infection in patients infected with human immunodeficiency virus (HIV). CD4+ lymphocyte counts have been found to be a marker of HIV disease progression. This study focused on determining the spectrum of Candida isolates in urine, stool, and oral spe...

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Bibliographic Details
Published in:Libyan journal of medicine 2013-01, Vol.8 (1), p.20322
Main Authors: Esebelahie, Newton O, Enweani, Ifeoma B, Omoregie, Richard
Format: Article
Language:English
Subjects:
Adult
Antiretroviral Therapy, Highly Active
Candida - isolation & purification
Candidiasis - complications
Candidiasis - epidemiology
CD4 Lymphocyte Count
Female
HIV Infections - complications
Humans
Male
Nigeria - epidemiology
Tertiary Care Centers
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Summary:Candidiasis is the commonest opportunistic fungal infection in patients infected with human immunodeficiency virus (HIV). CD4+ lymphocyte counts have been found to be a marker of HIV disease progression. This study focused on determining the spectrum of Candida isolates in urine, stool, and oral specimens among HIV patients in a tertiary hospital. A total of 300 subjects comprising of 200 HIV patients and 100 non-HIV subjects were used for this study. Three samples (urine, stool, and oral swab) were collected from each subject. Each specimen was processed using standard microbiological techniques and emergent Candida isolates were identified with CHROMagar™ Candida and sugar fermentation tests. The overall prevalence of Candida colonisation among HIV patients was 52.5%. HAART-naive patients had a significantly higher prevalence (OR = 3.65; 95% CI = 2.03-6.56; p
ISSN:1819-6357
DOI:10.3402/ljm.v8i0.20322