Whole‐genome sequencing approaches for conservation biology: Advantages, limitations and practical recommendations

Whole‐genome resequencing (WGR) is a powerful method for addressing fundamental evolutionary biology questions that have not been fully resolved using traditional methods. WGR includes four approaches: the sequencing of individuals to a high depth of coverage with either unresolved or resolved haplo...

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Bibliographic Details
Published in:	Molecular ecology 2017-10, Vol.26 (20), p.5369-5406
Main Authors:	Fuentes‐Pardo, Angela P., Ruzzante, Daniel E.
Format:	Article
Language:	English
Subjects:	Biological Evolution Biology Computing costs Conservation biology Conservation genetics Conservation of Natural Resources - methods Conserved sequence Deoxyribonucleic acid DNA DNA sequencing Gene Frequency Genetic diversity genetic variation Genetics Genetics, Population genome Genomes Genomic Library Genomics - methods Genotype Haplotypes High-Throughput Nucleotide Sequencing low‐coverage sequencing management mixing Mutation Nuclear electric power generation Phenotype Polymorphism, Single Nucleotide Pool‐seq Population Density population genomics Regulatory sequences sequence analysis Sequence Analysis, DNA - methods Single-nucleotide polymorphism surveys whole‐genome sequencing Wildlife conservation wildlife management
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