Isolation and characterization of DNA probes from a flow-sorted human chromosome 8 library that detect restriction fragment length polymorphism (RFLP)

We have used a recombinant DNA library constructed from flow-sorted human chromosome 8 as a source of single-copy human probes. These probes have been screened for restriction fragment length polymorphism (RFLP) by hybridization to Southern transfers of genomic DNA from five unrelated individuals. W...

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Bibliographic Details
Published in:American journal of human genetics 1986-12, Vol.39 (6), p.744-750
Main Authors: WOOD, S, STARR, T. V, SHUKIN, R. J
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chromatin. Chromosome
Chromosomes, Human, Pair 8
DNA, Recombinant - isolation & purification
Female
Fundamental and applied biological sciences. Psychology
Genetic Linkage
Genetic Markers
Humans
Male
Molecular and cellular biology
Molecular genetics
Nucleic Acid Hybridization
Pedigree
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Repetitive Sequences, Nucleic Acid
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