Transition Metal Free C–N Bond Forming Dearomatizations and Aryl C–H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent

We outline a simple protocol that accesses directly unprotected secondary amines by intramolecular C–N bond forming dearomatization or aryl C–H amination. The method is dependent on the generation of a potent electrophilic aminating agent released by in situ deprotection of O-Ts activated N-Boc hydr...

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Bibliographic Details
Published in:Journal of the American Chemical Society 2017-10, Vol.139 (40), p.14005-14008
Main Authors: Farndon, Joshua J, Ma, Xiaofeng, Bower, John F
Format: Article
Language:English
Subjects:
amination
chemical bonding
Communication
Lewis acids
protocols
secondary amines
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