The effect of maternal obesity on fetal biometry, body composition, and growth velocity

Introduction: The aim of this secondary analysis was to investigate the relationship between maternal body mass index (BMI) and fetal biometry, body composition, and velocity measurements at 28 and 36 weeks gestation. Materials and methods: The current analysis involves 911 overweight or obese women...

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Published in:The journal of maternal-fetal & neonatal medicine 2020-07, Vol.33 (13), p.2216-2226
Main Authors: O'Brien, Cecelia M., Louise, Jennie, Deussen, Andrea, Grivell, Rosalie, Dodd, Jodie M.
Format: Article
Language:English
Subjects:
Adiposity
Adult
body composition
Body Mass Index
Female
Fetal Development
fetal growth
Fetal Weight
Humans
obesity
Obesity, Maternal
Pregnancy
Ultrasonography, Prenatal
velocity
Waist Circumference
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Summary:Introduction: The aim of this secondary analysis was to investigate the relationship between maternal body mass index (BMI) and fetal biometry, body composition, and velocity measurements at 28 and 36 weeks gestation. Materials and methods: The current analysis involves 911 overweight or obese women who were randomized to the Standard Care group of the LIMIT randomized trial. Results: The fetus of women with Class 3 obesity (BMI ≥ 40.0) showed the greatest increase in all biometry z-scores, abdominal area (AA), and abdominal fat mass (AFM) compared with women classified as overweight (BMI 25.0-29.9). In women with Class 3 obesity, AA velocity was increased by 0.035 cm 2 (0.004, 0.066, p = .029) and the z-score velocity was increased by 0.238 (0.022, 0.453, p = .03). Estimated fetal weight (EFW) velocity for women with Class 3 obesity was higher than that of overweight women by 2.028 g per day (0.861, 3.196, p
ISSN:1476-7058
1476-4954
DOI:10.1080/14767058.2018.1543658