Proportionate and Disproportionate Functional Mitral Regurgitation: A New Conceptual Framework That Reconciles the Results of the MITRA-FR and COAPT Trials

Traditional approaches to the characterization of secondary or functional mitral regurgitation (MR) have largely ignored the critical importance of the left ventricle (LV). We propose that patients with secondary MR represent a heterogenous group, which can be usefully subdivided based on understand...

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Bibliographic Details
Published in:	JACC. Cardiovascular imaging 2019-02, Vol.12 (2), p.353
Main Authors:	Grayburn, Paul A, Sannino, Anna, Packer, Milton
Format:	Article
Language:	English
Subjects:	Cardiac Catheterization Cardiovascular Agents - therapeutic use Clinical Decision-Making Echocardiography Heart Valve Prosthesis Implantation Heart Ventricles - diagnostic imaging Heart Ventricles - physiopathology Humans Mitral Valve - diagnostic imaging Mitral Valve - physiopathology Mitral Valve - surgery Mitral Valve Insufficiency - diagnostic imaging Mitral Valve Insufficiency - epidemiology Mitral Valve Insufficiency - physiopathology Mitral Valve Insufficiency - therapy Predictive Value of Tests Randomized Controlled Trials as Topic Risk Factors Severity of Illness Index Treatment Outcome Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - epidemiology Ventricular Dysfunction, Left - physiopathology Ventricular Dysfunction, Left - therapy Ventricular Function, Left
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