Central role of G protein Gαi2 and Gαi2 + vomeronasal neurons in balancing territorial and infant-directed aggression of male mice

Aggression is controlled by the olfactory system in many animal species. In male mice, territorial and infant-directed aggression are tightly regulated by the vomeronasal organ (VNO), but how diverse subsets of sensory neurons convey pheromonal information to limbic centers is not yet known. Here, w...

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Published in:	Proceedings of the National Academy of Sciences - PNAS 2019-03, Vol.116 (11), p.5135-5143
Main Authors:	Center for Integrative Physiology and Molecular Medicine, Universität des Saarlandes [Saarbrücken] = Saarland University [Saarbrücken], Keller, Matthieu, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Laboratory of Neurobiology, National Institute of Environmental Health Sciences [Durham, NC, USA] (NIEHS-NIH), National Institutes of Health [Bethesda, MD, USA] (NIH)-National Institutes of Health [Bethesda, MD, USA] (NIH), Institut National de la Recherche Agronomique (INRA), Birnbaumer, Lutz, Zufall, Frank, Leinders-Zufall, Trese, Chamero, Pablo, Trouillet, Anne-Charlotte, Weiss, Jan, Department of Physiology
Format:	Article
Language:	English
Subjects:	Ablation Aggression Agricultural sciences Amygdala Animal biology Animal production studies Animal species Animals Animals, Newborn Bioengineering Biological Sciences Biomarkers - metabolism Brain Brain - physiology Brain Mapping Chemoreception Cognitive Sciences Ecology, environment Female Gene Deletion GTP-Binding Protein alpha Subunit, Gi2 - metabolism Imaging Infants Life Sciences Limbic system Male Mice Mice, Inbred C57BL Mutation - genetics Neurobiology Neurons Neurons and Cognition Neuroscience Olfactory pathways Olfactory system Parental behavior PNAS Plus Preoptic area Proteins Psychology and behavior Reproductive Biology Sensory neurons Sensory Receptor Cells - metabolism Septum Sexual behavior Sexual Behavior, Animal Sexual reproduction Stria terminalis Symbiosis Territoriality Vertebrate Zoology Veterinary medicine and animal Health Vomeronasal organ Vomeronasal Organ - metabolism Vomeronasal system Zootechny
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