Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9 Gene Expression in Hematological Disorders

The radial spatial positioning of individual gene loci within interphase nuclei has been associated with up- and downregulation of their expression. In cancer, the genome organization may become disturbed due to chromosomal abnormalities, such as translocations or deletions, resulting in the reposit...

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Bibliographic Details
Published in:Cancers 2019-04, Vol.11 (4)
Main Authors: Federico, Concetta, Owoka, Temitayo, Ragusa, Denise, Sturiale, Valentina, Caponnetto, Domenica, Leotta, Claudia Giovanna, Bruno, Francesca, Foster, Helen A, Rigamonti, Silvia, Giudici, Giovanni, Cazzaniga, Giovanni, Bridger, Joanna M, Sisu, Cristina, Saccone, Salvatore, Tosi, Sabrina
Format: Article
Language:English
Online Access:Get full text
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