Predictors of blood pressure control in patients with resistant hypertension after intensive management in two expert centres: the Brussels-Torino experience

Background: Management of resistant hypertension (RHTN) is challenging and often implies the use of complex polypharmacy and interventional therapies. The main objectives of this study were (i) to describe the characteristics of patients with RHTN referred to two expert centres; (ii) to identify pre...

Full description

Saved in:
Bibliographic Details
Published in:Blood pressure 2019-09, Vol.28 (5), p.336-344
Main Authors: Pappaccogli, Marco, Di Monaco, Silvia, Georges, Coralie M.G., Petit, Géraldine, Eula, Elisabetta, Ritscher, Sabrina, Lengelé, Jean-Philippe, Fanelli, Elvira, Severino, Francesca, Renkin, Jean, Avataneo, Valeria, Wallemacq, Pierre, Toennes, Stefan W., de Timary, Philippe, Rabbia, Franco, Persu, Alexandre
Format: Article
Language:English
Subjects:
Adult
Aged
Antihypertensive Agents - pharmacology
Antihypertensive Agents - therapeutic use
arterial stiffness
Blood Pressure - drug effects
Cardiovascular Diseases - prevention & control
drug adherence
Electronic Health Records
expression of emotions
Female
Follow-Up Studies
Humans
Hypertension - drug therapy
Hypertension - etiology
Hypertension - physiopathology
Hypertension - psychology
Male
Middle Aged
polypharmacy
Predictive Value of Tests
psychological profile
Resistant hypertension
Risk Factors
Stress, Psychological - complications
target organ damage
Vascular Stiffness - drug effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Management of resistant hypertension (RHTN) is challenging and often implies the use of complex polypharmacy and interventional therapies. The main objectives of this study were (i) to describe the characteristics of patients with RHTN referred to two expert centres; (ii) to identify predictors of blood pressure (BP) control after intensive management. Methods: We reviewed electronic medical files of all patients referred for RHTN to the Brussels and Torino centres, and extracted detailed clinical data, informations on drug adherence and psychological profile. All patients with confirmed diagnosis of RHTN, according to office and ambulatory BP monitoring (ABPM) measurements, were considered eligible. Results: 313 patients (51% men; age: 56 ± 12 years; office BP 177/98 mmHg; 24-hour ABPM 153/90 mmHg) were included. At the end of follow-up (median: 2 years [1-4]), only 26% of patients (n = 81) reached BP control. When compared to patients remaining resistant, patients eventually controlled had lower pulse pressure (71 vs. 82 mmHg, p 
ISSN:0803-7051
1651-1999
DOI:10.1080/08037051.2019.1633908