Protective Association Between Calcium Channel Blocker Use and Breast Cancer Recurrence in Postsurgical Women: A Population‐Based Case‐Control Study in Taiwan

Neoadjuvant chemotherapy induces metastasis of residual breast cancers through activation of tumor‐associated macrophages. Previous studies have indicated that calcium channel blockers (CCBs) exert anti‐inflammatory and antimigratory effects on macrophages via attenuating Ca2+ entry into macrophages...

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Bibliographic Details
Published in:Journal of clinical pharmacology 2020-06, Vol.60 (6), p.785-792
Main Authors: Shih, Jui‐Hu, Kao, Li‐Ting, Chung, Chi‐Hsiang, Liao, Guo‐Shiou, Fann, Li‐Yun, Chien, Wu‐Chien, Li, I‐Hsun
Format: Article
Language:English
Subjects:
Breast cancer
Breast surgery
calcium channel blockers
Calcium influx
Cell activation
Chemotherapy
Inflammation
Macrophages
Mastectomy
Metastases
Metastasis
Population studies
Population-based studies
prevention
recurrence
Surgery
tumor‐associated macrophages
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