Combination of large volume sample stacking with polarity switching and cyclodextrin electrokinetic chromatography (LVSS-PS-CDEKC) for the determination of selected preservatives in pharmaceuticals

In this study, a large volume sample stacking (LVSS) with polarity switching (PS) and cyclodextrin electrokinetic chromatography (CDEKC) method has been developed for the simultaneous separation and determination of 8 preservatives: methylparaben (MP), ethylparaben (EP), propylparaben (PP), butylpar...

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Bibliographic Details
Published in:Talanta (Oxford) 2020-05, Vol.211, p.120673, Article 120673
Main Authors: Pieckowski, Michał, Kowalski, Piotr, Bączek, Tomasz
Format: Article
Language:English
Subjects:
4-hydroxybenzoic acid
alpha-cyclodextrin
benzoic acid
chromatography
detection limit
drugs
Electrokinetic chromatography
electrolytes
electrophoresis
Highly-sulfated cyclodextrin
Large volume sample stacking
methylparaben
On-line preconcentration techniques
Preservative quantification
preservatives
quality control
Quality control of pharmaceuticals
sorbic acid
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