Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review

IMPORTANCE: The pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents an unprecedented challenge to identify effective drugs for prevention and treatment. Given the rapid pace of scientific discovery and clinical dat...

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Bibliographic Details
Published in:JAMA 2020-05, Vol.323 (18), p.1824-1836
Main Authors: Sanders, James M, Monogue, Marguerite L, Jodlowski, Tomasz Z, Cutrell, James B
Format: Article
Language:English
Subjects:
Adenosine Monophosphate - analogs & derivatives
Adenosine Monophosphate - therapeutic use
Adrenal Cortex Hormones - therapeutic use
Alanine - analogs & derivatives
Alanine - therapeutic use
Amides - therapeutic use
Angiotensin
Angiotensin Receptor Antagonists - therapeutic use
Angiotensin-converting enzyme inhibitors
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Antiviral Agents - therapeutic use
Azithromycin - therapeutic use
Betacoronavirus - drug effects
Betacoronavirus - physiology
Chloroquine - therapeutic use
Clinical trials
Coronaviridae
Coronavirus Infections - drug therapy
Coronavirus Infections - epidemiology
Coronaviruses
Corticoids
Corticosteroids
COVID-19
Enzyme inhibitors
FDA approval
Humans
Hydroxychloroquine - therapeutic use
Immunoglobulins - therapeutic use
Immunologic Factors - therapeutic use
Immunomodulators
Indoles - therapeutic use
Influenza
Lopinavir - therapeutic use
Medical treatment
Oseltamivir
Oseltamivir - therapeutic use
Pandemics
Peptidyl-dipeptidase A
Pneumonia, Viral - drug therapy
Pneumonia, Viral - epidemiology
Public health
Pyrazines - therapeutic use
Respiratory diseases
Ribavirin - therapeutic use
Ritonavir - therapeutic use
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Therapeutic targets
Viral diseases
Viruses
Withholding Treatment
Online Access:Request full text
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