Rationale and design of a prospective, observational, multicentre study on the safety and efficacy of apixaban for the prevention of thromboembolism in adults with congenital heart disease and atrial arrhythmias: the PROTECT-AR study

IntroductionThe risk for stroke in adults with congenital heart disease (ACHD) is increased, especially in the setting of commonly ensuing atrial arrhythmias (AA), namely atrial fibrillation, atrial flutter or intra-atrial re-entrant tachycardia. Data are limited regarding treatment with non-vitamin...

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Bibliographic Details
Published in:BMJ open 2020-09, Vol.10 (9), p.e038012
Main Authors: Kartas, Anastasios, Doundoulakis, Ioannis, Ntiloudi, Despoina, Koutsakis, Athanasios, Kosmidis, Diamantis, Rampidis, Georgios, Apostolopoulou, Sotiria, Frogoudaki, Alexandra, Tzifa, Afrodite, Avramidis, Dimosthenis, Ntzoyvara, Olga, Liori, Sotiria, Mousiama, Tereza, Mouratoglou, Sophia Anastasia, Karvounis, Haralambos, Giannakoulas, George
Format: Article
Language:English
Subjects:
Adult
Anticoagulants
Anticoagulants - adverse effects
anticoagulation
Atrial Fibrillation - complications
Atrial Fibrillation - drug therapy
Cardiac arrhythmia
Cardiovascular disease
Cardiovascular Medicine
Cohort Studies
Committees
Congenital diseases
congenital heart disease
Disease prevention
Epidemiology
Epistaxis
Greece
Heart
Heart Defects, Congenital
Humans
Medical imaging
Non-pharmacological intervention
Patients
Prospective Studies
protocols & guidelines
Pulmonary embolisms
Pyrazoles
Pyridones - adverse effects
Stroke
Stroke - prevention & control
Thromboembolism
Thromboembolism - etiology
Thromboembolism - prevention & control
Thrombosis
Treatment Outcome
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