Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is among the most frequent causes of disability and death worldwide. Current treatment approaches involve achieving rapid reperfusion either pharmacologically or surgically, both of which are time‐sensitive; moreov...

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Bibliographic Details
Published in:Medicinal research reviews 2022-01, Vol.42 (1), p.259-305
Main Authors: Tuo, Qing‐zhang, Zhang, Shu‐ting, Lei, Peng
Format: Article
Language:English
Subjects:
Apoptosis
Cell death
Drug development
Ferroptosis
ischemic stroke
neuronal death
neuroprotection
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