The effect of lymph node ratio on survival in non-small-cell lung cancer

The aim of this study was to evaluate the effect of prognostic factors and lymph node ratio (LNR) on survival in patients with resected non-small-cell lung cancer (NSCLC). Data from 421 patients with NSCLC who underwent complete resection between 2009 and 2015 were evaluated retrospectively. LNR was...

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Published in:Acta chirurgica belgica 2023-01, Vol.123 (1), p.36-42
Main Authors: Sezen, Celal Bugra, Kalafat, Cem Emrah, Doğru, Mustafa Vedat, Aker, Cemal, Erdogu, Volkan, Saydam, Ozkan, Metin, Muzaffer
Format: Article
Language:English
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Aged
Carcinoma, Non-Small-Cell Lung - pathology
Humans
Lung cancer staging
Lung Neoplasms - pathology
Lymph Node Excision
Lymph Node Ratio
Lymph Nodes - pathology
Neoplasm Staging
non-small cell lung cancer
Prognosis
Retrospective Studies
survival
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container_start_page 36
container_title Acta chirurgica belgica
container_volume 123
creator Sezen, Celal Bugra
Kalafat, Cem Emrah
Doğru, Mustafa Vedat
Aker, Cemal
Erdogu, Volkan
Saydam, Ozkan
Metin, Muzaffer
description The aim of this study was to evaluate the effect of prognostic factors and lymph node ratio (LNR) on survival in patients with resected non-small-cell lung cancer (NSCLC). Data from 421 patients with NSCLC who underwent complete resection between 2009 and 2015 were evaluated retrospectively. LNR was defined as the ratio of positive lymph nodes to the total number of lymph nodes removed. Associations between overall survival (OS) and LNR, node (N) status, and histopathologic status were evaluated. The 5-year survival rate was 42.5% among all patients and 26.6% for patients aged 65 years or older. In the multivariate analysis, age ≥65 years, advanced-stage disease, non-squamous cell carcinomas, pN status, and having multiple-station pN2 and multiple-station pN1 disease were found to be poor prognostic factors (p 
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source Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list)
subjects Aged
Carcinoma, Non-Small-Cell Lung - pathology
Humans
Lung cancer staging
Lung Neoplasms - pathology
Lymph Node Excision
Lymph Node Ratio
Lymph Nodes - pathology
Neoplasm Staging
non-small cell lung cancer
Prognosis
Retrospective Studies
survival
title The effect of lymph node ratio on survival in non-small-cell lung cancer
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