Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial

•What is the primary question addressed by this study?The main goal was to evaluate the efficacy and side effects of low-dose lithium to treat agitation in Alzheimer's disease (AD).•What is the main finding of this study?In 77 patients with AD and agitation randomized to lithium or placebo in a...

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Bibliographic Details
Published in:The American journal of geriatric psychiatry 2022, Vol.30 (1), p.32-42
Main Authors: Devanand, D.P., Crocco, Elizabeth, Forester, Brent P., Husain, Mustafa M., Lee, Seonjoo, Vahia, Ipsit V., Andrews, Howard, Simon-Pearson, Laura, Imran, Nadia, Luca, Luminita, Huey, Edward D., Deliyannides, Deborah A., Pelton, Gregory H.
Format: Article
Language:English
Subjects:
Aggressiveness
Agitation
Alzheimer Disease - complications
Alzheimer Disease - diagnosis
Alzheimer Disease - drug therapy
Alzheimer's disease
Behavior problems
Clinical outcomes
Clinical research
Clinical trials
Delusions
Dementia
Disease
Double-Blind Method
Double-blind studies
Efficacy
Humans
Irritability
Lithium
Lithium - therapeutic use
Lithium Compounds - adverse effects
Mania
Measures
Medical treatment
Patients
Placebo effect
Psychiatry
Psychomotor Agitation - drug therapy
Psychomotor Agitation - etiology
Psychomotor Agitation - psychology
Psychosis
Safety
Serum
Treatment Outcome
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