Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant, primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic heterogeneity, and protection by the blood brain barrier (BBB) have posed great treatment challenges. The standard treatme...

Full description

Saved in:
Bibliographic Details
Published in:Pharmacological research 2021-09, Vol.171, p.105780-105780, Article 105780
Main Authors: Wu, Wei, Klockow, Jessica L., Zhang, Michael, Lafortune, Famyrah, Chang, Edwin, Jin, Linchun, Wu, Yang, Daldrup-Link, Heike E.
Format: Article
Language:English
Subjects:
Animals
Antineoplastic Agents - therapeutic use
Brain Neoplasms - drug therapy
Chemotherapy
Drug Resistance, Neoplasm
Glioblastoma
Glioblastoma - drug therapy
Humans
Immunotherapy
Nanotherapy
Radiotherapy
Targeted therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!