The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating in the motor neuron to action potentials in the muscle fiber. The consideration of contributing factors to skeletal m...

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Bibliographic Details
Published in:International journal of molecular sciences 2021-07, Vol.22 (15), p.8058
Main Authors: Iyer, Shama R., Shah, Sameer B., Lovering, Richard M.
Format: Article
Language:English
Subjects:
Aging
Aging - pathology
Animals
Congenital diseases
Extracellular matrix
Gene expression
Humans
Morphology
Muscle, Skeletal - pathology
Muscular dystrophy
Musculoskeletal system
Mutation
Nervous system
Neuromuscular Diseases - pathology
Neuromuscular Junction - pathology
Pathology
Pathophysiology
Proteins
Review
Roles
Sarcopenia
Synapses
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