The methods and advances of adaptive immune receptors repertoire sequencing

The adaptive immune response is a powerful tool, capable of recognizing, binding to, and neutralizing a vast number of internal and external threats via T or B lymphatic receptors with widespread sets of antigen specificities. The emergence of high-throughput sequencing technology and bioinformatics...

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Bibliographic Details
Published in:Theranostics 2021-01, Vol.11 (18), p.8945-8963
Main Authors: Liu, Hongmei, Pan, Wenjing, Tang, Congli, Tang, Yujie, Wu, Haijing, Yoshimura, Akihiko, Deng, Yan, He, Nongyue, Li, Song
Format: Article
Language:English
Subjects:
Adaptive Immunity
Adaptive Immunity - genetics
Adaptive Immunity - immunology
Adaptive Immunity - physiology
Antigens
B-Lymphocytes
B-Lymphocytes - metabolism
Bias
Binding sites
Computational Biology
Computational Biology - methods
Data analysis
Disease
Genes
High-Throughput Nucleotide Sequencing
High-Throughput Nucleotide Sequencing - methods
Humans
Immune response
Immune system
Lymphocyte receptors
Lymphocytes
Medical diagnosis
Methods
Raw materials
Receptors, Immunologic
Receptors, Immunologic - genetics
Research Paper
Single-Cell Analysis
Single-Cell Analysis - methods
T-Lymphocytes
T-Lymphocytes - metabolism
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