MR-based proton density fat fraction (PDFF) of the vertebral bone marrow differentiates between patients with and without osteoporotic vertebral fractures

Summary The bone marrow proton density fat fraction (PDFF) assessed with MRI enables the differentiation between osteoporotic/osteopenic patients with and without vertebral fractures. Therefore, PDFF may be a potentially useful biomarker for bone fragility assessment. Introduction To evaluate whethe...

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Bibliographic Details
Published in:Osteoporosis international 2022-02, Vol.33 (2), p.487-496
Main Authors: Gassert, F. T., Kufner, A., Gassert, F. G., Leonhardt, Y., Kronthaler, S., Schwaiger, B. J., Boehm, C., Makowski, M. R., Kirschke, J. S., Baum, T., Karampinos, D. C., Gersing, A. S.
Format: Article
Language:English
Subjects:
Biomarkers
Bone Density
Bone imaging
Bone marrow
Bone Marrow - diagnostic imaging
Bone mineral density
Cancellous bone
Computed tomography
Endocrinology
Energy
Female
Fractures
Humans
Lumbar Vertebrae - diagnostic imaging
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Original
Original Article
Orthopedics
Osteoporosis
Osteoporotic Fractures - diagnostic imaging
Osteoporotic Fractures - etiology
Protons
Regression analysis
Rheumatology
Spinal Fractures - diagnostic imaging
Spinal Fractures - etiology
Spine (lumbar)
Vertebrae
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