Eastern Association for the Surgery of Trauma Multicenter Trial: Comparison of pre-injury antithrombotic use and reversal strategies among severe traumatic brain injury patients

Trauma teams are often faced with patients on antithrombotic (AT) drugs, which is challenging when bleeding occurs. We sought to compare the effects of different AT medications on head injury severity and hypothesized that AT reversal would not improve mortality in severe traumatic brain injury (TBI...

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Bibliographic Details
Published in:The journal of trauma and acute care surgery 2022-01, Vol.92 (1), p.88-92
Main Authors: Yorkgitis, Brian K., Tatum, Danielle M., Taghavi, Sharven, Schroeppel, Thomas J., Noorbakhsh, Matthew R., Philps, Frances Hite, Bugaev, Nikolay, Mukherjee, Kaushik, Bellora, Mellody, Ong, Adrian W., Ratnasekera, Asanthi, Nordham, Kristen D., Carrick, Matthew M., Haan, James M., Lightwine, Kelly L., Lottenberg, Lawrence, Borrego, Robert, Cullinane, Daniel C., Berne, John D., Rodriguez Mederos, Dalier, Hayward, Thomas Z., Kerwin, Andy J., Crandall, Marie
Format: Article
Language:English
Subjects:
Aged
Anticoagulant Reversal Agents - administration & dosage
Aspirin - adverse effects
Aspirin - therapeutic use
Brain Injuries, Traumatic - complications
Brain Injuries, Traumatic - diagnosis
Brain Injuries, Traumatic - mortality
Brain Injuries, Traumatic - therapy
Cardiovascular Diseases - drug therapy
Cardiovascular Diseases - epidemiology
Comorbidity
Deamino Arginine Vasopressin - administration & dosage
Factor Xa Inhibitors - adverse effects
Factor Xa Inhibitors - therapeutic use
Female
Fibrinolytic Agents - adverse effects
Fibrinolytic Agents - classification
Fibrinolytic Agents - therapeutic use
Hemorrhage - etiology
Hemorrhage - mortality
Hemorrhage - therapy
Hospital Mortality
Humans
Male
Platelet Transfusion - statistics & numerical data
Risk Assessment - methods
Risk Assessment - statistics & numerical data
Trauma Severity Indices
Treatment Outcome
United States - epidemiology
Warfarin - adverse effects
Warfarin - therapeutic use
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