Comparing Rod-Mediated Dark Adaptation in Older Adults before and after Cataract Surgery

Studies on age-related macular degeneration often use rod-mediated dark adaptation (RMDA) to evaluate macular functional health, studying eyes with cataract and pseudophakic eyes within the same sample. We examine a poorly understood issue-whether rod intercept time (RIT), a measure of RMDA, changes...

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Published in:Current eye research 2023-05, Vol.48 (5), p.512-517
Main Authors: Tanaya, Tarushi, Swain, Thomas A., Clark, Mark E., Swanner, Jason C., Lolley, Virginia R., Callahan, Michael A., McGwin, Gerald, Owsley, Cynthia
Format: Article
Language:English
Subjects:
Aged
Capsule Opacification
cataract
Cataract - complications
Cataract Extraction
cataract surgery
Dark Adaptation
Humans
Rod-mediated dark adaptation
Visual Acuity
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Summary:Studies on age-related macular degeneration often use rod-mediated dark adaptation (RMDA) to evaluate macular functional health, studying eyes with cataract and pseudophakic eyes within the same sample. We examine a poorly understood issue-whether rod intercept time (RIT), a measure of RMDA, changes after cataract surgery and intraocular lens (IOL) insertion as compared to RIT before cataract surgery. Cataract may serve as a filter reducing photo-bleach magnitude prior to surgery, biasing RMDA interpretation. A pre-/post-cataract surgery design was used. Persons with nuclear sclerotic and/or cortical cataract per the electronic health record were enrolled. Prior to cataract surgery, visual acuity, RMDA, and the LOCS III classification documenting cataract presence/severity were measured. Thirty days after surgery (mean), visual acuity and RMDA were repeated, followed by fundus photos to document macular health. Twenty-four participants (mean age 72.7 years, standard deviation 5.6) enrolled. All eyes had nuclear sclerotic and nuclear color cataract; 68% had cortical cataract. All IOLs were monofocal with 21 having blue blocking characteristics and 3 had clear IOLs. Most eyes had higher RIT post-surgery (15.6 min, SD 6.7) as compared to pre-surgery (13.7 min, SD 6.4), p = 0.0006, meaning that RMDA was slower post-surgery. Eyes with moderate cataract (
ISSN:0271-3683
1460-2202
1460-2202
DOI:10.1080/02713683.2023.2171438