Dupilumab in the treatment of severe uncontrolled chronic rhinosinusitis with nasal polyps ( CRSwNP ): A multicentric observational Phase IV real‐life study ( DUPIREAL )

Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with significant morbidity and reduced health-related quality of life. Findings from clinical trials have demonstrated the effectiveness of dupilumab in CRSwNP, although real-world evidence is still limited. This Phase IV real-life, obs...

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Published in:	Allergy (Copenhagen) 2023-10, Vol.78 (10), p.2669-2683
Main Authors:	De Corso, Eugenio, Pasquini, Ernesto, Trimarchi, Matteo, La Mantia, Ignazio, Pagella, Fabio, Ottaviano, Giancarlo, Garzaro, Massimiliano, Pipolo, Carlotta, Torretta, Sara, Seccia, Veronica, Cantone, Elena, Ciofalo, Andrea, Lucidi, Daniela, Fadda, Gian Luca, Pafundi, Pia Clara, Settimi, Stefano, Montuori, Claudio, Anastasi, Francesca, Pagliuca, Giulio, Ghidini, Angelo, Cavaliere, Carlo, Maffei, Marianna, Bussu, Francesco, Gallo, Stefania, Canevari, Frank Rikki Mauritz, Paludetti, Gaetano, Galli, Jacopo
Format:	Article
Language:	English
Subjects:	adrenal cortex hormones Clinical trials Comorbidity Corticosteroids hypersensitivity Monoclonal antibodies Morbidity nose Olfaction Patients Polyps Quality of life Rhinitis Rhinosinusitis Sinusitis smell Steroid hormones Surgery
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