Non-cell-autonomous cancer progression from chromosomal instability

Chromosomal instability (CIN) is a driver of cancer metastasis 1 – 4 , yet the extent to which this effect depends on the immune system remains unknown. Using ContactTracing—a newly developed, validated and benchmarked tool to infer the nature and conditional dependence of cell–cell interactions fro...

Full description

Saved in:
Bibliographic Details
Published in:Nature (London) 2023-08, Vol.620 (7976), p.1080-1088
Main Authors: Li, Jun, Hubisz, Melissa J., Earlie, Ethan M., Duran, Mercedes A., Hong, Christy, Varela, Austin A., Lettera, Emanuele, Deyell, Matthew, Tavora, Bernardo, Havel, Jonathan J., Phyu, Su M., Amin, Amit Dipak, Budre, Karolina, Kamiya, Erina, Cavallo, Julie-Ann, Garris, Christopher, Powell, Simon, Reis-Filho, Jorge S., Wen, Hannah, Bettigole, Sarah, Khan, Atif J., Izar, Benjamin, Parkes, Eileen E., Laughney, Ashley M., Bakhoum, Samuel F.
Format: Article
Language:English
Subjects:
13/21
13/31
13/51
14
14/1
14/63
38
38/91
631/250/256/2515
631/67/322
631/67/327
631/67/580
631/80/103
Benchmarking
Breast cancer
Cell Communication
Cell interactions
Cells
Cellular stress response
Chromosomal Instability
Chromosomes
Colorectal cancer
Colorectal Neoplasms - drug therapy
Colorectal Neoplasms - genetics
Colorectal Neoplasms - immunology
Colorectal Neoplasms - pathology
Contact tracing
CRISPR
Disease Progression
Endoplasmic reticulum
Endoplasmic Reticulum Stress
Genomic instability
Humanities and Social Sciences
Humans
Immune system
Interferon Type I - immunology
Ligands
Lymphocytes
Melanoma
Melanoma - drug therapy
Melanoma - genetics
Melanoma - immunology
Melanoma - pathology
Metastases
Metastasis
Micronuclei
multidisciplinary
Neoplasm Metastasis
Neoplasms - genetics
Neoplasms - immunology
Neoplasms - pathology
Science
Science (multidisciplinary)
Signal Transduction
Tachyphylaxis
Transcriptomics
Triple Negative Breast Neoplasms - drug therapy
Triple Negative Breast Neoplasms - genetics
Triple Negative Breast Neoplasms - immunology
Triple Negative Breast Neoplasms - pathology
Tumor Microenvironment
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!