Chitobiose exhibited a lipid-lowering effect in ob/ob−/− mice via butyric acid enrolled liver–gut crosstalk

Chitobiose (COS 2 ) efficiently lowers lipids in vivo and facilitates butyric acid enrichment during human fecal fermentation. However, whether COS 2 can interact with butyric acid to generate a hypolipidemic effect remains unclear. This study examined the hypolipidemic mechanism of COS 2 involving...

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Bibliographic Details
Published in:Bioresources and bioprocessing 2023-11, Vol.10 (1), p.79-16, Article 79
Main Authors: Zhuang, Xinye, Zhao, Mengyao, Ji, Xiaoguo, Yang, Sihan, Yin, Hao, Zhao, Liming
Format: Article
Language:English
Subjects:
Accumulation
Biochemical Engineering
Butyric acid
Chemistry
Chemistry and Materials Science
Chitobiose
Environmental Engineering/Biotechnology
Fatty liver
Fermentation
Hydrogen bonding
Hydrogen bonds
Industrial and Production Engineering
Lipid β-oxidation
Lipids
Liver
Liver diseases
Liver–gut axis signaling
Metabolites
Non-alcoholic fatty liver disease
Oxidation
Sodium oleate
Structural analysis
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