Parallel detection of multiple biomarkers in a point-of-care-competent device for the prediction of exacerbations in chronic inflammatory lung disease

Sudden aggravations of chronic inflammatory airway diseases are difficult-to-foresee life-threatening episodes for which advanced prognosis-systems are highly desirable. Here we present an experimental chip-based fluidic system designed for the rapid and sensitive measurement of biomarkers prognosti...

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Bibliographic Details
Published in:Scientific reports 2024-06, Vol.14 (1), p.12830-12, Article 12830
Main Authors: Röckendorf, Niels, Ramaker, Katrin, Gaede, Karoline, Tappertzhofen, Kristof, Lunding, Lars, Wegmann, Michael, Horbert, Peter, Weber, Karina, Frey, Andreas
Format: Article
Language:English
Subjects:
631/250/127
692/53/2423
692/699/1785/31
Airway management
Antibodies
Arrays
Asthma
Asthma - diagnosis
Bacterial diseases
Bacterial infections
Biomarkers
C-reactive protein
C-Reactive Protein - analysis
C-Reactive Protein - metabolism
Chronic obstructive pulmonary disease
Cloning
Cytokines
Cytokines - metabolism
Health care
Humanities and Social Sciences
Humans
Immunology
Interleukin 6
Interleukin 8
Lab-On-A-Chip Devices
Lung diseases
multidisciplinary
Pathogens
Patients
Point-of-Care Systems
Prognosis
Pulmonary Disease, Chronic Obstructive - diagnosis
Reagents
Research centers
Respiratory tract diseases
Science
Science (multidisciplinary)
Streptococcus infections
Streptococcus pneumoniae - isolation & purification
Tumor Necrosis Factor-alpha - analysis
Tumor necrosis factor-TNF
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