Identification of senescent cell subpopulations by CITE‐seq analysis

Cellular senescence, a state of persistent growth arrest, is closely associated with aging and age‐related diseases. Deciphering the heterogeneity within senescent cell populations and identifying therapeutic targets are paramount for mitigating senescence‐associated pathologies. In this study, prot...

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Bibliographic Details
Published in:Aging cell 2024-11, Vol.23 (11), p.e14297-n/a
Main Authors: Abdelmohsen, Kotb, Mazan‐Mamczarz, Krystyna, Munk, Rachel, Tsitsipatis, Dimitrios, Meng, Qiong, Rossi, Martina, Pal, Apala, Shin, Chang Hoon, Martindale, Jennifer L., Piao, Yulan, Fan, Jinshui, Yanai, Hagai, De, Supriyo, Beerman, Isabel, Gorospe, Myriam
Format: Article
Language:English
Subjects:
Aging
Antibodies
CD44 antigen
CD73 antigen
Cell cycle
Cell surface
Cellular Senescence - genetics
CITE‐seq
Dipeptidyl-peptidase IV
Epitopes
G1 phase
Genes
Humans
Ionizing radiation
Mass spectroscopy
Population studies
Proteins
proteome
Radiation
Senescence
Single-Cell Analysis - methods
single‐cell transcriptome
surface proteins
surfaceome
Therapeutic targets
Transcriptomes
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