Cerium Oxide-Loaded Exosomes Derived From Regulatory T Cells Ameliorate Inflammatory Bowel Disease by Scavenging Reactive Oxygen Species and Modulating the Inflammatory Response

Abnormal immune homeostasis, which leads to the accumulation of reactive oxygen species (ROS) and an inflammatory response, plays a crucial role in accelerating the progression of inflammatory bowel disease (IBD). The lack of targeted therapeutic strategies significantly hampers the efficacy of clin...

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Bibliographic Details
Published in:	Journal of inflammation research 2025-01, Vol.18, p.4395-4408
Main Authors:	Yue, Simei, Gong, Lingjiao, Tan, Yulin, Zhang, Xiaodan, Liao, Fei
Format:	Article
Language:	English
Subjects:	Animal models Anti-inflammatory agents Antioxidants Apoptosis Cell culture Cells Cerium cerium oxide Cerium oxides Development and progression Dextran Dextran sulfate Epithelial cells Exosomes Flow cytometry Fluorides Free radicals Gastrointestinal diseases Homeostasis Hydroxyl radicals Immunofluorescence Immunohistochemistry Immunoregulation Inflammatory bowel disease Inflammatory bowel diseases Intestine Labeling Lymphocytes Lymphocytes T Monoclonal antibodies Morphology Nanoparticles Original Research Oxidative stress Quantitative analysis Reactive oxygen species regulatory T cells Software T cells Transmission electron microscopy Western blotting
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