Alternatives Integrating Omics Approaches for the Advancement of Human Skin Models: A Focus on Metagenomics, Metatranscriptomics, and Metaproteomics

The human skin microbiota, a complex community of bacterial, fungal, and viral organisms, plays a crucial role in maintaining skin homeostasis and regulating host-pathogen interactions. Dysbiosis within this microbial ecosystem has been implicated in various dermatological conditions, including acne...

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Bibliographic Details
Published in:Microorganisms (Basel) 2025-07, Vol.13 (8), p.1771
Main Authors: Fernández-Carro, Estibaliz, Letsiou, Sophia, Tsironi, Stella, Chaniotis, Dimitrios, Ciriza, Jesús, Beloukas, Apostolos
Format: Article
Language:English
Subjects:
Acne
Analysis
Atopic dermatitis
Bacteria
Dermatitis
Disease
Dysbacteriosis
Ecosystems
Endothelial cells
Gene expression
Genomes
Health aspects
Homeostasis
Host-pathogen interactions
human skin models
Inflammation
Metabolism
Metabolites
Metabolomics
Metagenomics
metaproteomics
metatranscriptomics
Microbiomes
Microbiota
Microbiota (Symbiotic organisms)
Microenvironments
Microorganisms
Molecular modelling
Pathogens
Psoriasis
Puberty
Review
Seborrheic dermatitis
Skin
Skin diseases
skin microbiome
Therapeutic targets
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