PhyloMed: a phylogeny-based test of mediation effect in microbiome

Microbiome data from sequencing experiments contain the relative abundance of a large number of microbial taxa with their evolutionary relationships represented by a phylogenetic tree. The compositional and high-dimensional nature of the microbiome mediator challenges the validity of standard mediat...

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Bibliographic Details
Published in:Genome Biology 2023-04, Vol.24 (1), p.72-72, Article 72
Main Authors: Hong, Qilin, Chen, Guanhua, Tang, Zheng-Zheng
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Bioinformatics
Biomedical and Life Sciences
Composite null hypothesis
Euclidean space
Evolutionary Biology
genome
Human Genetics
Hypotheses
Life Sciences
Mediation analysis
Method
Microbial Genetics and Genomics
Microbiome
Microbiomes
Microbiota
Phylogenetic tree
Phylogenetics
Phylogeny
Plant Genetics and Genomics
Taxonomy
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