The potential ecological risk of veterinary pharmaceuticals from swine wastewater on freshwater aquatic environment

• Published in: Water environment research 2023-01, Vol.95 (1), p.e10833-n/a
• Main Authors: Udebuani, Angela Chika, Pereao, Omoniyi, Akharame, Michael Ovbare, Fatoki, Olalekan Siyanbola, Opeolu, Beatrice Olutoyin
• Format: Article
• Language: English
• Subjects: Animals; Anti-Bacterial Agents; ecological risk; Ecosystem; effluent; Fresh Water - chemistry; freshwater ecosystem; Ivermectin - toxicity; piggery; Salicylic Acid; Swine; Tetracyclines; Veterinary Drugs - toxicity; veterinary pharmaceuticals; Wastewater - toxicity; Water Pollutants, Chemical - chemistry
• ISSN: 1061-4303; 1554-7531
• DOI: 10.1002/wer.10833

The impact of pharmaceutical residue transport in the aquatic ecosystem has become an increasing subject of environmental interest due to the inherent bioactivity of trace levels of antibiotics and the negative environmental and public health impact. In this study, three veterinary pharmaceuticals including tetracycline, ivermectin, and salicylic acid were investigated in a piggery effluent from Western Cape, South Africa. Three freshwater organisms' taxonomic groups (Pseudokirchneriella subcapitata, Daphnia magna, and Tetrahymena thermophila) were used to determine the ecological risk of different treated piggery effluent concentration range of 1%, 10%, and 20% and a cocktail mixture of veterinary pharmaceuticals of environmental concerns. The average concentration of veterinary pharmaceuticals was in the range of 47.35, 7.19, and 1.46 μg L−1 for salicylic acid, chloro‐tetracycline, and ivermectin, respectively. P. subcapitata exposed to 20% piggery wastewater effluent at 24‐ and 48‐h EC50 showed a toxicity value of 14.2% and 13.6% (v/v), respectively. The study established the ecological risk of the test compounds as low to medium risk for low‐level dose and low concentrations of piggery effluent. The relative sensitivity ranking of the taxa drawn is microalgae > protozoa > Cladocera. The study results demonstrated that a high dose of piggery effluent and mixtures of veterinary pharmaceutical can pose a high risk in freshwater ecosystems. Practitioner Points Transport processes of veterinary antibiotics into the environment were investigated. Dilution effect of the veterinary pharmaceutical on the antibiotic levels exists. High dose of piggery effluent presented an ecological risk. Pharmaceutical residue transport in the aquatic ecosystem has negative environmental and public health impact. The ecological risk for low‐level dose and low concentrations of piggery effluent is low to medium risk. High‐level dose of piggery effluent and mixtures of veterinary pharmaceutical can pose high risk in freshwater ecosystems.