Profitability of Chemically Cross-Linked Collagen Scaffold Production Using Bovine Pericardium: Revaluing Waste from the Meat Industry for Biomedical Applications

The meat industry generates a large amount of waste that can be used to create useful products such as bio-implants, which are usually expensive. In this report, we present an economic analysis of a continuous process for large-scale chemically cross-linked collagen scaffold (CCLCS) production in a...

Full description

Saved in:
Bibliographic Details
Published in:Polymers 2023-06, Vol.15 (13), p.2797
Main Authors: Cruz Bosques, José Arturo de la, Ibarra Sánchez, José de Jesús, Mendoza-Novelo, Birzabith, Segovia-Hernandez, Juan Gabriel, Molina-Guerrero, Carlos Eduardo
Format: Article
Language:English
Subjects:
Biomedical materials
Cattle
Collagen
Crosslinking
Economic analysis
Ethylenediaminetetraacetic acid
Feasibility studies
Meat industry
Meat processing industry
Pericardium
Pricing
Production costs
Profitability
Quality assurance
Quality control
R&D
Raw materials
Research & development
Scaffolds
Simulation
Skin
Surfactants
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The meat industry generates a large amount of waste that can be used to create useful products such as bio-implants, which are usually expensive. In this report, we present an economic analysis of a continuous process for large-scale chemically cross-linked collagen scaffold (CCLCS) production in a Mexican context. For this purpose, three production capacities were simulated using SuperPro Designer v 12.0: 5, 15, and 25 × 10 bovine pericardium units (BPU) per month as process feedstock. Data indicated that these capacities produced 2.5, 7.5, and 12.5 kg of biomesh per batch (per day), respectively. In addition, Net Unit Production Costs (NUPC) of 784.57, 458.94, and 388.26 $USD.kg were obtained, correspondingly, with selling prices of 0.16 ± 0.078 USD.cm , 0.086 ± 0.043 USD.cm , and 0.069 ± 0.035 USD.cm , in the same order. We found that these selling prices were significantly lower than those in the current market in Mexico. Finally, distribution of costs associated with the process followed the order: raw materials > facility-dependent > labor > royalties > quality analysis/quality control (QA/QC) > utilities. The present study showed the feasibility of producing low-cost and highly profitable CCLCS with a relatively small investment. As a result, the circular bioeconomy may be stimulated.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym15132797