EGFR is a potential dual molecular target for cancer and Alzheimer’s disease

Many researchers are attempting to identify drugs that can be repurposed as effective therapies for Alzheimer’s disease (AD). Several recent studies have highlighted epidermal growth factor receptor (EGFR) inhibitors approved for use as anti-cancer drugs as potential candidates for repurposing as AD...

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Bibliographic Details
Published in:Frontiers in pharmacology 2023-08, Vol.14, p.1238639
Main Authors: Choi, Hee-Jeong, Jeong, Yoo Joo, Kim, Jieun, Hoe, Hyang-Sook
Format: Article
Language:English
Subjects:
Alzheimer's disease
Angiogenesis
Animal models
Antineoplastic drugs
Cancer
Cell growth
Cell proliferation
Cognitive ability
Drug development
EGFR
EGFR inhibitor
Epidermal growth factor
Epidermal growth factor receptors
Kinases
learning and memory
Mutation
Neurodegenerative diseases
Pathology
Pharmacology
Therapeutic applications
Tyrosine kinase inhibitors
β-Amyloid
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