Sociodemographic disparities associated with advanced stages and distant metastatic breast cancers at diagnosis in Indonesia: a cross-sectional study

• Published in: Annals of medicine and surgery 2023-09, Vol.85 (9), p.4211-4217
• Main Authors: Setyawan, IG Budhi, Kurnia, Dian, Setiaji, Kunta, Anwar, Sumadi Lukman, Purwanto, Deni J., Azhar, Yohana, Budijitno, Selamat, Suprabawati, Desak Gede Agung, Priyono, Sasongko Hadi, Siregar, Bintang Abadi, Indriawan, Ramses, Tripriadi, Effif Syofra, Umar, Mulawan, Pieter, John SLA, Yarso, Kristanto Yuli, Hermansyah, Dedy, Wibisana, IGN Gunawan, Harahap, Wirsma Arif, Gautama, Walta, Achmad, Dimyati
• Format: Article
• Language: English
• Subjects: Original Research
• ISSN: 2049-0801; 2049-0801
• DOI: 10.1097/MS9.0000000000001030

BackgroundThe global health burden of breast cancer is increasing with 5-year survival rates being much shorter in low-income and middle-income countries. Sociodemographic and clinical disparities in early cancer detection affect long-term outcome. MethodsThe authors compared social, demographic, and pathological characteristics associated with metastatic and late stages of breast cancer diagnosis using data collected from a special registry developed by Perhimpunan Bedah Onkologi Indonesia (PERABOI) in 2015. ResultsOf 4959 patients recruited in this study, 995 women (20.1%) were diagnosed with metastatic breast cancer. Lower education status and living in rural areas were significantly associated with Stage IV at diagnosis [odds ratio (OR)=1.256, 95% CI=1.093-1.445, P=0.001; and OR=1.197, 95% CI=1.042-1.377, P=0.012; respectively). Main complaints other than lump (ulceration, breast pain, and discharge) and occupation as a housewife were also associated with the presentation of metastatic diseases (OR=2.598, 95% CI=2.538-3.448, P