Racial disparities in care escalation for postpartum hemorrhage requiring transfusion

• Published in: American journal of obstetrics & gynecology MFM 2023-06, Vol.5 (6), p.100938-100938, Article 100938
• Main Authors: Guan, Carolyn S., Boyer, Theresa M., Darwin, Kristin C., Henshaw, Chelsea, Michos, Erin D., Lawson, Shari, Vaught, Arthur J.
• Format: Article
• Language: English
• Subjects: antihemorrhagic intervention; blood loss; Blood Transfusion; Female; Hemostatics; Humans; hysterectomy; maternal morbidity; obstetrics; postpartum hemorrhage; Postpartum Hemorrhage - diagnosis; Postpartum Hemorrhage - epidemiology; Postpartum Hemorrhage - therapy; Pregnancy; racial disparities; retrospective cohort study; Retrospective Studies; transfusion; United States - epidemiology
• ISSN: 2589-9333; 2589-9333
• DOI: 10.1016/j.ajogmf.2023.100938

Postpartum hemorrhage is a leading cause of maternal morbidity and mortality in the United States and disproportionately affects pregnant persons of color. This study aimed to identify the demographic and obstetrical characteristics of those who received different levels of antihemorrhagic intervention in the setting of severe postpartum hemorrhage requiring blood transfusion. This was a retrospective cohort study of patients with documented postpartum hemorrhage (estimated blood loss of ≥1000 mL) and blood product transfusion. Moreover, 3 levels of antihemorrhagic intervention were defined as follows: level 1, administration of uterotonics only; level 2, performance of a procedure (ie, B-Lynch suture, O'Leary stitch, Bakri balloon, dilation and curettage, laceration repair, or embolization); and level 3, hysterectomy. Maternal demographics, obstetrical characteristics, and comorbidities were extracted from electronic health records. Ordinal logistic regression was used to estimate the odds of higher intervention levels adjusting for maternal demographic and obstetrical characteristics. Of note, 365 patients were included in this study, with a racial or ethnic composition of 30% White, 42% Black, 18% Hispanic, and 10% other. Moreover, 233 patients (64%) received level 1 intervention, 98 patients (27%) received level 2 intervention, and 34 patients (9%) received level 3 intervention. Patients receiving higher levels of intervention were more likely to have greater estimated blood loss (P