Diagnostic value of high-frequency ultrasound (HFUS) in evaluation of subcutaneous lesions

It is unknown whether high-frequency ultrasound (HFUS) can evaluate invisible subcutaneous lesions. We aimed to investigate the diagnostic value of HFUS in invisible subcutaneous lesions. Patients with invisible subcutaneous lesions were prospectively recruited from two centres. Before undergoing bi...

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Bibliographic Details
Published in:Skin research and technology 2023-09, Vol.29 (9), p.e13464
Main Authors: Miao, Yao, Ren, Wei-Wei, Yang, Fei-Yue, Li, Liang, Wu, Ling, Dan Shan, Dan, Chen, Zi-Tong, Wang, Li-Fan, Wang, Qiao, Guo, Le-Hang
Format: Article
Language:English
Subjects:
Accuracy
Biopsy
Cysts
Dermatofibrosarcoma protuberans
Diagnosis
Diagnostic systems
Epidermal Cyst - diagnostic imaging
Fibroids
Hair Diseases
Hemangioma
Hemangioma - diagnostic imaging
Histiocytoma, Benign Fibrous
Humans
Leiomyoma
Lesions
Lipoma
Neurofibroma
Original
Patients
Pilomatrixoma
Skin Neoplasms - diagnostic imaging
Ultrasonic imaging
Ultrasound
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Summary:It is unknown whether high-frequency ultrasound (HFUS) can evaluate invisible subcutaneous lesions. We aimed to investigate the diagnostic value of HFUS in invisible subcutaneous lesions. Patients with invisible subcutaneous lesions were prospectively recruited from two centres. Before undergoing biopsy or surgery, each lesion was independently evaluated by two clinicians. One provides a clinical diagnosis by only clinical examination and the other provides an integrated diagnosis by combining clinical examination and HFUS information. Diagnoses were classified as correct, wrong, and indeterminate. A total of 391 lesions from 355 patients were enrolled, including 225 epidermoid cysts, 77 lipomas, 25 pilomatrixomas, 21 haemangiomas, 19 dermatofibromas, 11 dermatofibrosarcoma protuberans (DFSP), 7 neurofibromas, and 6 leiomyomas. Using pathological results as the gold standard, diagnostic performance was compared. The number of correct diagnoses increased from 185 (47.3%) by clinical examination alone to 316 (80.8%) after the addition of HFUS (P 
ISSN:0909-752X
1600-0846
1600-0846
DOI:10.1111/srt.13464