Status of Biofilm Production and Vancomycin Resistance in Enterococcus in the Rural Population of Mathura, India

IntroductionHospital-acquired or nosocomial infections caused by the rapidly emerging bacteria vancomycin-resistant enterococci can be dangerous and even fatal. Therefore, this study aimed to investigate the presence of enterococci in various clinical specimens along with their vancomycin resistance...

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Published in:Curēus (Palo Alto, CA) CA), 2023-08, Vol.15 (8), p.e43351-e43351
Main Authors: Kumar, Dinesh, Mehrishi, Priya, Faujdar, Sameer Singh, Chaudhary, Bajarangi Lal, Panwar, Sonu
Format: Article
Language:English
Subjects:
Age groups
Antibiotics
Biofilms
Catheters
Drug resistance
Infectious Disease
Lavage
Males
Microorganisms
Nosocomial infections
Penicillin
Urine
Vagina
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Summary:IntroductionHospital-acquired or nosocomial infections caused by the rapidly emerging bacteria vancomycin-resistant enterococci can be dangerous and even fatal. Therefore, this study aimed to investigate the presence of enterococci in various clinical specimens along with their vancomycin resistance status and biofilm-producing capabilities.MethodsA total of 164 Enterococcus species were isolated and further included in this study. Isolation and identification were done by the standard bacteriological procedure, antibiotic susceptibility testingwas done by clinical laboratory standard guidelines, and biofilm production test was done by microtiter plate methods.ResultsAmong the total of 164 isolates, Enterococcus faecalis constituted 60.97% and Enterococcus faecium constituted 39.02%. Maximum isolates were from urine samples. The prevalence of vancomycin-resistant Enterococcus was 6.70%, and 18.29% of Enterococcus isolates were biofilm producers. The sensitivity among the biofilm producers was maximum for linezolid (87.33%), followed by teicoplanin (86.43%) and vancomycin (79.64%).ConclusionHigh prevalence of enterococci was found in urine samples and biofilm producers Enterococcus isolates were more antibiotic-resistant than non-biofilm producers.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.43351