63 Repeated Administration of Sucrose in Hospitalized Preterm Infants and Neurodevelopment at 18 Months

Background Preterm neonates, often hospitalized in the neonatal intensive care units (NICU), undergo multiple skin-breaking procedures. To minimize procedural pain, these infants frequently receive repeated administration of sucrose of varying concentrations and doses. Repetitive procedural pain has...

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Published in:Paediatrics & child health 2023-09, Vol.28 (Supplement_1), p.e28-e29
Main Authors: Bueno, Mariana, Stevens, Bonnie, Ballantyne, Marilyn, Campbell-Yeo, Marsha, Estabrooks, Carole, Gibbins, Sharyn, Harrison, Denise, McNair, Carol, Riahi, Shirine, Squires, Janet, Synnes, Anne, Taddio, Anna, Victor, Charles, Yamada, Janet
Format: Article
Language:English
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Abstract / Résumés
Gestational age
Newborn babies
Premature babies
Sucrose
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Summary:Background Preterm neonates, often hospitalized in the neonatal intensive care units (NICU), undergo multiple skin-breaking procedures. To minimize procedural pain, these infants frequently receive repeated administration of sucrose of varying concentrations and doses. Repetitive procedural pain has been associated with neurodevelopmental consequences, but long-term effects of repeated sucrose administration and volume are unknown. Objectives Our goal was to examine the association of total volume of sucrose over the NICU stay and neurodevelopment of preterm neonates at 18 months corrected gestational age (CGA). Design/Methods A prospective longitudinal observational study was conducted in four level-III Canadian NICUs. Infants
ISSN:1205-7088
1918-1485
DOI:10.1093/pch/pxad055.063