Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience

• Published in: Curēus (Palo Alto, CA) CA), 2023-09, Vol.15 (9), p.e45304-e45304
• Main Authors: Kumar, Rupesh, Halder, Vikram, Ghosh, Soumitra, Thingnam, Shyam, Singh, Harkant, Mishra, Anand K, Mahajan, Sachin, Aggarwal, Pankaj, Dutta, Aduri Raja S, Mishra, Amit
• Format: Article
• Language: English
• Subjects: Cardiac/Thoracic/Vascular Surgery; Cardiology; Cardiovascular disease; Congenital diseases; Down syndrome; Heart; Medical education; Mortality; Postoperative period; Pulmonary hypertension; Standard deviation; Therapeutics; Thoracic surgery
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.45304

Background/aim: Surgical repair techniques and management of patients with atrioventricular septal defect (AVSD) have progressed over the last few decades. Early and definitive interventions have become the choice of treatment for these patients. Based on this background, we aimed to review the early and mid-term outcomes of primary AVSD repair.Methods: A total of 53 patients with a mean age of 3.45 ± 5.67 years underwent definitive repair for AVSD between January 2014 and June 2021. The clinical data including age, type of defect, associated co-anomalies, symptoms, pulmonary hypertension, etc. were collected and assessed retrospectively. Mitral regurgitation (MR) as a clinical outcome was assessed at 0, 1, 2, and 5 years.Results: Among the recruited patients, 35 (66.1%) were male and 18 (33.9%) were female. Of 53 patients, repair for the complete defect was done in 38 (71.69%) patients, repair for intermediate/partial defect was done in 15 (23.1%) patients, and one patient underwent repair for incomplete type. Other associated co-anomalies were anterior mitral leaflet (12 (22.6%)), atrial and ventricular septal defect (VSD) (30 (56.6%)), and patent ductus arteriosus (PDA) (11 (20.8%)). Different procedures for surgical repair included patch closure, cleft repair, and polytetrafluoroethylene (PTFE) VSD closure. After repair, the mean follow-up period was 46.73 ± 27.37 months. Overall mortality was 3.78% (2/53), and two patients underwent reintervention due to symptomatic severe MR.Conclusions: A definitive and timely correction of AVSD shows satisfactory early and mid-term results.